ව ස ප ර ස න හ වත ප රත ම ත රල ය හ ර ම නය ADH ආර ජ න න ව ස ප ර ස න AVP හ ආර ජ ප ර ස න යන ව න හ ඳ න ව න න synthesized as a

වේසොප්‍රෙසින්, හෙවත් ප්‍රතිමෞත්‍රල්‍ය හෝර්මෝනය (ADH), ආර්ජිනීන් වේසොප්‍රෙසින් (AVP) හෝ ආර්ජිප්‍රෙසින්, යනුවෙන් හැඳින්වෙන්නේ synthesized as a in in the , and is converted to AVP. It then travels down the of that cell, which terminates in the , and is released from into the circulation in response to extracellular fluid (). AVP has two primary functions. First, it increases the amount of solute-free water reabsorbed back into the circulation from the filtrate in the of the . Second, AVP constricts , which increases and raises arterial .




Systematic () name
1-{[(4R,7S,10S,13S,16S,19R)-19-Amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-L-p rolyl-L-arginylglycinamide
Clinical data
	?
Pharmacokinetic data
	1%
	ප්‍රධාන වශයෙන් අක්මාව සහ වෘක්කවල
	10–20 මිනිත්තු
	මූත්‍ර
Identifiers
	11000-17-2^Y[]
	BA01
	CID 644077
	2168
	DB00067
	559126^Y
	Y4907O6MFD^Y
	D00101^Y
	CHEBI:9937 ^Y
	CHEMBL373742 ^Y
	Antidiuretic hormone (ADH); arginine vasopressin (AVP); argipressin
Chemical data
Formula	C₄₆H₆₅N₁₅O₁₂₂
InChI=1S/C46H65N15O12S2 /c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14-15-35(48)63)55-41(69)31(18-24-6-2-1-3-7-24)58-42(70)30(57-38(27)66)19-25-10-12-26(62)13-11-25/h1-3,6-7,10-13,27-34,62H,4-5,8-9,14-23,47H2,(H2,48,63)(H2,49,64)(H2,50,65)(H,54,67)(H,55,69)(H,56,72)(H,57,66)(H,58,70)(H,59,68)(H,60,71)(H4,51,52,53)/t27-,28-,29-,30-,31-,32-,33-,34-/m0/s1^Y Key:KBZOIRJILGZLEJ-LGYYRGKSSA-N^Y
Physical data
	1.6±0.1 g/cm³

arginine vasopressin

Identifiers

vasopressin-neurophysin 2-copeptinADHcopeptinargipressinvasopressin-neurophysin II-copeptinprepro-arginine-vasopressin-neurophysin IIAVP-NPIIAVPvasopressinarginine-vasopressinantidiuretic hormoneneurohypophysealprepro-AVP-NP II

External IDs

[1]

pattern

More reference expression data

Species

Human

Mouse


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RefSeq (mRNA)


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RefSeq (protein)


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Location (UCSC)

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PubMed search

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Wikidata

View/Edit Human

A third function is possible. Some AVP may be released directly into the from the hypothalamus, and may play an important role in , and , and maternal responses to stress.

Vasopressin induces differentiation of stem cells into cardiomyocytes and promotes heart muscle homeostasis.

It has a very short half-life, between 16–24 minutes.

ආශ්‍රේයයන්

Anderson DA (2012). Dorland's Illustrated Medical Dictionary (32nd ed.). Elsevier. ISBN .
Marieb, Elaine (2014). Anatomy & physiology. Glenview, IL: Pearson Education, Inc. ISBN . {{}}: Unknown parameter |name-list-format= ignored ()
Caldwell HK, Young WS III (2006). "Oxytocin and Vasopressin: Genetics and Behavioral Implications". In Lajtha A, Lim R (eds.). Handbook of Neurochemistry and Molecular Neurobiology: Neuroactive Proteins and Peptides (3rd ed.). Berlin: Springer. pp. 573–607. ISBN . {{}}: Unknown parameter |chapterurl= ignored ()
Babar SM (October 2013). "SIADH associated with ciprofloxacin". The Annals of Pharmacotherapy. 47 (10): 1359–63. doi:10.1177/1060028013502457. PMID 24259701.
Insel TR (March 2010). "The challenge of translation in social neuroscience: a review of oxytocin, vasopressin, and affiliative behavior". Neuron (English බසින්). 65 (6): 768–79. doi:10.1016/j.neuron.2010.03.005. PMC 2847497. PMID 20346754.{{}}: CS1 maint: unrecognized language ()
Costa A, Rossi E, Scicchitano BM, Coletti D, Moresi V, Adamo S (September 2014). "Neurohypophyseal Hormones: Novel Actors of Striated Muscle Development and Homeostasis". review. European Journal of Translational Myology. 24 (3): 3790. doi:10.4081/bam.2014.3.217. PMC 4756744. PMID 26913138.

වැඩිදුර කියවීමට

Rector, Floyd C.; Brenner, Barry M. (2004). (7th ed.). Philadelphia: Saunders. ISBN . 2016-03-03 දින මුල් පිටපත වෙතින් සංරක්ෂණය කරන ලදී. සම්ප්‍රවේශය 2020-09-07. {{}}: Unknown parameter |name-list-format= ignored ()

[Dorlands-1] Anderson DA (2012). Dorland's Illustrated Medical Dictionary (32nd ed.). Elsevier. ISBN .

[Marieb-2] Marieb, Elaine (2014). Anatomy & physiology. Glenview, IL: Pearson Education, Inc. ISBN . {{}}: Unknown parameter |name-list-format= ignored ()

[isbn0-387-30348-0-3] Caldwell HK, Young WS III (2006). "Oxytocin and Vasopressin: Genetics and Behavioral Implications". In Lajtha A, Lim R (eds.). Handbook of Neurochemistry and Molecular Neurobiology: Neuroactive Proteins and Peptides (3rd ed.). Berlin: Springer. pp. 573–607. ISBN . {{}}: Unknown parameter |chapterurl= ignored ()

[babar2013-4] Babar SM (October 2013). "SIADH associated with ciprofloxacin". The Annals of Pharmacotherapy. 47 (10): 1359–63. doi:10.1177/1060028013502457. PMID 24259701.

[5] Insel TR (March 2010). "The challenge of translation in social neuroscience: a review of oxytocin, vasopressin, and affiliative behavior". Neuron (English බසින්). 65 (6): 768–79. doi:10.1016/j.neuron.2010.03.005. PMC 2847497. PMID 20346754.{{}}: CS1 maint: unrecognized language ()

[Costa_2014-6] Costa A, Rossi E, Scicchitano BM, Coletti D, Moresi V, Adamo S (September 2014). "Neurohypophyseal Hormones: Novel Actors of Striated Muscle Development and Homeostasis". review. European Journal of Translational Myology. 24 (3): 3790. doi:10.4081/bam.2014.3.217. PMC 4756744. PMID 26913138.